Actualización de las recomendaciones de medidas de prevención y aislamiento frente al sars-cov-2 en las unidades de diálisis: un posicionamiento de la sociedad española de nefrología Update of the prevention and isolation measure recommendations against SARS-COV-2 in dialysis units of Spain: a position paper of the Spanish Society of Nephrology Council

La pandemia por SARS-CoV-2 ha evolucionado a lo largo de los dos últimos años tanto por la aparición de nuevas variantes como por el desarrollo y administración de la vacunación. La Junta Directiva de la Sociedad Española de Nefrología (S.E.N.) considera necesario actualizar las recomendaciones vigentes de protección y aislamiento para los pacientes con necesidad de terapia renal sustitutiva en programas de diálisis, adecuándolas al contexto epidemiológico actual, situación que ha motivado la realización del siguiente documento con recomendaciones.

The Impact of Age on Mortality in Chronic Haemodialysis Popu-Lation with COVID-19.

Age and chronic kidney disease have been described as mortality risk factors for coronavirus disease 2019 (COVID-19). Currently, an important percentage of patients in haemodialysis are elderly. Herein, we investigated the impact of age on mortality among haemodialysis patients with COVID-19. Data was obtained from the Spanish COVID-19 chronic kidney disease (CKD) Working Group Registry. From 18 March 2020 to 27 August 2020, 930 patients on haemodialysis affected by COVID-19 were included in the Registry. A total of 254 patients were under 65 years old and 676 were 65 years or older (elderly group). Mortality was 25.1% higher (95% CI: 22.2-28.0%) in the elderly as compared to the non-elderly group. Death from COVID-19 was increased 6.2-fold in haemodialysis patients as compared to the mortality in the general population in a similar time frame. In the multivariate Cox regression analysis, age (hazard ratio (HR) 1.59, 95% CI: 1.31-1.93), dyspnea at presentation (HR 1.51, 95% CI: 1.11-2.04), pneumonia (HR 1.74, 95% CI: 1.10-2.73) and admission to hospital (HR 4.00, 95% CI: 1.83-8.70) were identified as independent mortality risk factors in the elderly haemodialysis population. Treatment with glucocorticoids reduced the risk of death (HR 0.68, 95% CI: 0.48-0.96). In conclusion, mortality is dramatically increased in elderly haemodialysis patients with COVID-19. Our results suggest that this high risk population should be prioritized in terms of protection and vaccination.